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Chemical Compound Review

Mycaminose     (2R,3S,4S,5R)-3- dimethylamino-2,4,5...

Synonyms: AG-K-85863, CHEBI:32569, AC1L4NQP, CTK4J5127, AR-1E9982, ...
 
 
 
 
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Disease relevance of Mycaminose

  • Chalcomycin, a 16-membered macrolide antibiotic made by the bacterium Streptomyces bikiniensis, contains a 2,3-trans double bond and the neutral sugar D-chalcose in place of the amino sugar mycaminose found in most other 16-membered macrolides [1].

References

  1. Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae. Ward, S.L., Hu, Z., Schirmer, A., Reid, R., Revill, W.P., Reeves, C.D., Petrakovsky, O.V., Dong, S.D., Katz, L. Antimicrob. Agents Chemother. (2004) [Pubmed]
 
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