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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Chemical Compound Review

AG-K-61358     2-oxobut-3-enoic acid

Synonyms: CHEBI:74021, AC1L4RYS, CTK1H2680, AR-1F2353, AR-1F2354, ...
 
 
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Disease relevance of Vinylglyoxylate

  • Therefore, vinylglyoxylate may be a normal metabolite in mammals which at elevated concentrations may contribute to the in vivo toxicity of canavanine and of some of the other above-mentioned amino acids [1].

References

  1. Conversion of canavanine to alpha-keto-gamma-guanidinooxybutyrate and to vinylglyoxylate and 2-hydroxyguanidine. Hollander, M.M., Reiter, A.J., Horner, W.H., Cooper, A.J. Arch. Biochem. Biophys. (1989) [Pubmed]
 
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