Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

CHEMBL431453 (2S)-2-[[(5S,8S)-5-[[(2S,3R)- 1-[(2S)-2...

Synonyms: SureCN9038881, AR-1J3429, Ro-091437, AC1L4UU4, Ro 09-1437, ...

Angehrn, P. et al.

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Disease relevance of Cyclothialidine

Cyclothialidine (1, Ro 09-1437) is a potent DNA gyrase inhibitor that was isolated from Streptomyces filipinensis NR0484 and is a member of a new family of natural products [1].

References

New antibacterial agents derived from the DNA gyrase inhibitor cyclothialidine. Angehrn, P., Buchmann, S., Funk, C., Goetschi, E., Gmuender, H., Hebeisen, P., Kostrewa, D., Link, H., Luebbers, T., Masciadri, R., Nielsen, J., Reindl, P., Ricklin, F., Schmitt-Hoffmann, A., Theil, F.P. J. Med. Chem. (2004) [Pubmed]

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