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Chemical Compound Review

Phosphine E     9-(4-aminophenyl)-2-methyl- acridin-3...

Synonyms: Phosphine 3R, AG-K-09892, NSC-75905, AC1L4VTF, NSC75905, ...
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High impact information on 9-(4-aminophenyl)-2-methyl-acridin-3-amine

  • Since these Nomarski-dense granules are positively stained by phosphine-3R, these results indicate that increased amounts of immunoreactive calmodulin appear associated with lamellar body surfaces when the cells are stimulated for secretion [1].
  • After more than 50 population doublings, the RLE-6T cells stained positive for cytokeratin, possessed alkaline phosphatase activity, and contained lipid-containing inclusion bodies (phosphine 3R staining); all characteristics of alveolar Type II cells [2].
  • We have devised, in the course of the current study, a double fluorescence technique as an observational method whereby microtubules were observed immunocytochemically and lipid droplets by a secondary fluorescence with phosphine E staining [3].
 

Analytical, diagnostic and therapeutic context of 9-(4-aminophenyl)-2-methyl-acridin-3-amine

References

  1. Localization of calmodulin in differentiating pulmonary type II epithelial cells. Hill, D.J., Wright, T.C., Andrews, M.L., Karnovsky, M.J. Lab. Invest. (1984) [Pubmed]
  2. Establishment of immortalized alveolar type II epithelial cell lines from adult rats. Driscoll, K.E., Carter, J.M., Iype, P.T., Kumari, H.L., Crosby, L.L., Aardema, M.J., Isfort, R.J., Cody, D., Chestnut, M.H., Burns, J.L. In Vitro Cell. Dev. Biol. Anim. (1995) [Pubmed]
  3. Immunocytochemistry of the Microtubules of fat-laden cells. Brown fat cells and adrenocortical cells in primary monolayer culture. Sugihara, H., Yonemitsu, N., Ohta, K., Miyabara, S., Nagayama, A. Histochemistry (1983) [Pubmed]
  4. Characterization of Clara and type II cells isolated from rat lung by fluorescence-activated flow cytometry. Martin, J., Dinsdale, D., White, I.N. Biochem. J. (1993) [Pubmed]
 
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