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Chemical Compound Review

N6-Me-dAdo     (2R,3S,5R)-2-(hydroxymethyl)- 5-(6...

Synonyms: N(6)-Me-Dado, SureCN548569, AG-J-17351, M2389_SIGMA, HG1034, ...
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High impact information on NSC 66392

  • The non-selective P2 receptor antagonist pyridoxalphosphate-6-azophenyl-2',4'-disulphonic acid, the P2Y1 receptor antagonist N6-methyl-2'-deoxyadenosine 3',5'-bisphosphate and the P2Y1 receptor-antibody itself inhibited the agonist-induced effects [1].
  • Competitive and selective antagonism of P2Y1 receptors by N6-methyl 2'-deoxyadenosine 3',5'-bisphosphate [2].

Anatomical context of NSC 66392


  1. P2Y receptor expression on astrocytes in the nucleus accumbens of rats. Franke, H., Krügel, U., Grosche, J., Heine, C., Härtig, W., Allgaier, C., Illes, P. Neuroscience (2004) [Pubmed]
  2. Competitive and selective antagonism of P2Y1 receptors by N6-methyl 2'-deoxyadenosine 3',5'-bisphosphate. Boyer, J.L., Mohanram, A., Camaioni, E., Jacobson, K.A., Harden, T.K. Br. J. Pharmacol. (1998) [Pubmed]
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