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Chemical Compound Review:

PubChem22012 4-amino-3-methyl-phenol

Synonyms: SureCN34069, CCRIS 8320, AG-E-90992, ACMC-209h2a, CHEBI:55546, ...

Eggenreich, K. et al., Ohkuma, Y. et al., Eggenreich, K. et al., Vandevoorde, S. et al.

Vandevoorde, Fowler,

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High impact information on NSC72170

An HPLC assay was set up to measure 4-amino-m-cresol, the hypothesised product of FAAH-catalysed VDM11 hydrolysis [1].
UV-visible and ESR spectroscopic studies have demonstrated that 4-amino-3-methylphenol is autoxidized to form the aminomethylphenoxyl radical and o-nitrosotoluene is reduced by NADH to the o-toluolhydronitroxide radical in the presence and absence of Cu(II) [2].
For the determination of two oxidation hair dyes, 4-amino-m-cresol (4-AC) and 5-amino-o-cresol (5-AC), a sensitive isocratic high performance liquid chromatography (HPLC) method using the reversed phase mode was developed [3].
Determination of 4-amino-m-cresol and 5-amino-o-cresol and metabolites in human keratinocytes (HaCaT) by high-performance liquid chromatography with DAD and MS detection [4].

Analytical, diagnostic and therapeutic context of NSC72170

Determination of 4-amino-m-cresol and 5-amino-o-cresol by high performance liquid chromatography and fluorescence derivatization using fluorescamine [3].

References

Inhibition of fatty acid amide hydrolase and monoacylglycerol lipase by the anandamide uptake inhibitor VDM11: evidence that VDM11 acts as an FAAH substrate. Vandevoorde, S., Fowler, C.J. Br. J. Pharmacol. (2005) [Pubmed]
Distinct mechanisms of oxidative DNA damage by two metabolites of carcinogenic o-toluidine. Ohkuma, Y., Hiraku, Y., Oikawa, S., Yamashita, N., Murata, M., Kawanishi, S. Arch. Biochem. Biophys. (1999) [Pubmed]
Determination of 4-amino-m-cresol and 5-amino-o-cresol by high performance liquid chromatography and fluorescence derivatization using fluorescamine. Eggenreich, K., Zach, E., Beck, H., Wintersteiger, R. J. Biochem. Biophys. Methods (2004) [Pubmed]
Determination of 4-amino-m-cresol and 5-amino-o-cresol and metabolites in human keratinocytes (HaCaT) by high-performance liquid chromatography with DAD and MS detection. Eggenreich, K., Golouch, S., Töscher, B., Beck, H., Kuehnelt, D., Wintersteiger, R. J. Biochem. Biophys. Methods (2004) [Pubmed]

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