Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

Isomaltohexose (2R,3S,4R,5R)-2,3,4,5- tetrahydroxy-6-[(2S...

Synonyms: AC1L4NUT, AR-1L8576, Isomaltohexaose

Howard, J.G. et al., Stein, K.E. et al., Moreno, C. et al.

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High impact information on Isomaltohexose

Similarly, CBA anti-Dex antibodies cross-reacted with both IM3 and IM6 coupled to bovine serum albumin (BSA), whereas C57BL anti-Dex antibodies cross-reacted with IM6-BSA and bound IM3-BSA only very poorly [1].
Characteristics of the T-dependent alpha(1 leads to 6) glucosyl (dextran) antibody response induced in mice with isomaltohexaose coupled to chicken gamma-globulin [2].
This response is distinguishable from the alpha1--3-linked specificity assayed by homologous sensitization in that: (a) it is totally suppressed in donors previously rendered tolerant of B512; (b) the PFC are sensitive to inhibition by B512 and isomaltohexaose [3].

References

The immune response to an isomaltohexosyl-protein conjugate, a thymus-dependent analogue of alpha(1 replaced by 6) dextran. Stein, K.E., Zopf, D.A., Johnson, B.M., Miller, C.B., Paul, W.E. J. Immunol. (1982) [Pubmed]
Characteristics of the T-dependent alpha(1 leads to 6) glucosyl (dextran) antibody response induced in mice with isomaltohexaose coupled to chicken gamma-globulin. Moreno, C., Hale, C., Hewett, R., Cussell, D. Eur. J. Immunol. (1979) [Pubmed]
Influence of molecular structure of the tolerogenicity of bacterial dextrans. III. Dissociation between tolerance and immunity to the alpha1--6- and alpha1--3-linked epitopes of dextran B1355. Howard, J.G., Courtenay, B.M., Vicari, G. Immunology (1975) [Pubmed]

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