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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Chemical Compound Review: 

SureCN14108398     5-amino-1-[(2R,3R,4S,5R)-5- (aminomethyl)-3...

Synonyms: AC1Q3NVL, GP-1-468, AR-1G6990, AC1L4U59, GP 1-468, ...
 
 
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Disease relevance of GP-1-468

 

Analytical, diagnostic and therapeutic context of GP-1-468

  • They were also added to the cardioplegic solution (10 mumol/L for GP-1-468, 5 mumol/L for GP-1-343, the active metabolite of GP-1-668) and were also given to recipient rats (20 mg/kg intravenously, 30 minutes before transplantation, so that the drugs were present during reperfusion) [1].

References

  1. Protection against injury during ischemia and reperfusion by acadesine derivatives GP-1-468 and GP-1-668. Studies in the transplanted rat heart. Galiñanes, M., Zhai, X., Bullough, D., Mullane, K.M., Hearse, D.J. J. Thorac. Cardiovasc. Surg. (1995) [Pubmed]
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