Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Chemical Compound Review:

AR-1K4323 1-piperidyl (4S)-4-amino-4-[[[(2S,3S)-2...

Synonyms: S-2337, AC1L4XW7, AC1Q68MZ, S 2337, Bz-Ile-glu(gamma-piperidyl)-gly-arg-pna

Erskine, J.G. et al., Lindhout, T. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on S 2337

The second-order rate constant of inhibition of factor Xa alone by antithrombin III as determined by using the synthetic peptide substrate S-2337 was found to be 1.1 X 10(6) M-1 min-1 [1].
From the regression line of the S 2337 factor X assay on the Thrombotest results, the comparable range for factor X amidolytic activity in well controlled anticoagulated patients was found to be 22.5-37.5% with this method [2].

References

Thrombin generation and inactivation in the presence of antithrombin III and heparin. Lindhout, T., Baruch, D., Schoen, P., Franssen, J., Hemker, H.C. Biochemistry (1986) [Pubmed]
Maintenance control of oral anticoagulant therapy by an automated chromogenic substrate assay of factor X. Erskine, J.G., Walker, I.D., Davidson, J.F. Clinical and laboratory haematology. (1982) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

Editor

Share