Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

AC1L4YFS (2S)-N-[(1S)-2-(4H-imidazol- 4-yl)-1-[[(2S)...

Synonyms: AR-1G9314, FT-0641478, AC1Q6PB3, Pglu-his-pro-2NA, Pyroglutamyl-histidyl-prolyl-2-naphthylamide

Friedman, T.C. et al.

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High impact information on Pglu-his-pro-2NA

Reports of a thyrotropin-releasing hormone-degrading enzyme with narrow specificity that cleaves the pGlu-His bond of this tripeptide led us to develop a coupled assay using pGlu-His-Pro-2NA as the substrate to measure this activity [1].

References

Delineation of a particulate thyrotropin-releasing hormone-degrading enzyme in rat brain by the use of specific inhibitors of prolyl endopeptidase and pyroglutamyl peptide hydrolase. Friedman, T.C., Wilk, S. J. Neurochem. (1986) [Pubmed]

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