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Chemical Compound Review

Men-10,573     benzyl2-[8-(2- aminocarbonylethyl)-14...

Synonyms: Men 10573, Men 10,573, AC1L52LB, L010021, 151911-03-4
 
 
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High impact information on Men 10573

  • 7. MEN 10,376 and the cyclic pseudopeptide MEN 10,573 antagonized in a competitive manner the response to [beta Ala8]NKA(4-10) in the ileum and colon.(ABSTRACT TRUNCATED AT 400 WORDS)[1]
  • The activity and selectivity of MEN 10,573 and MEN 10,612, novel cyclic pseudopeptides which are selective tachykinin NK-2 receptor antagonists is described, as compared to that of previously characterized linear and cyclic compounds [2].

References

  1. Comparison of tachykinin NK1 and NK2 receptors in the circular muscle of the guinea-pig ileum and proximal colon. Maggi, C.A., Patacchini, R., Meini, S., Quartara, L., Sisto, A., Potier, E., Giuliani, S., Giachetti, A. Br. J. Pharmacol. (1994) [Pubmed]
  2. MEN 10,573 and MEN 10,612, novel cyclic pseudopeptides which are potent tachykinin NK-2 receptor antagonists. Maggi, C.A., Quartara, L., Patacchini, R., Giuliani, S., Barbanti, G., Turini, D., Giachetti, A. Regul. Pept. (1993) [Pubmed]
 
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