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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review

NSC-10855     2-aminopentanedioic acid; 2,6...

Synonyms: NSC10855, SBB068595, AR-1J1187, AKOS015918392, AC1L5CH1, ...
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Disease relevance of Lysine glutamate

  • In particular, lysine-glutamate salt bridges between residues on helices alpha(2) and alpha(4), which were observed in both human and E. coli proteins, are not present in the chimeric protein [1].

High impact information on Lysine glutamate

  • METHODS: The patients were infused with two liters of a commercially-available nutritive amino acid solution (containing approximately 2.25 g/liter lysine-glutamate and 2.50 g/liter arginine), whereas 75 control patients received the same volume of saline (quantification of organ and tumor kinetics from conjugate whole-body views by ROI technique) [2].


  1. Solution structure and dynamics of the human-Escherichia coli thioredoxin chimera: insights into thermodynamic stability. Dangi, B., Dobrodumov, A.V., Louis, J.M., Gronenborn, A.M. Biochemistry (2002) [Pubmed]
  2. Reduction of renal uptake of monoclonal antibody fragments by amino acid infusion. Behr, T.M., Becker, W.S., Sharkey, R.M., Juweid, M.E., Dunn, R.M., Bair, H.J., Wolf, F.G., Goldenberg, D.M. J. Nucl. Med. (1996) [Pubmed]
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