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Chemical Compound Review

DMAQ-B1     2,5-dihydroxy-3-[2-(2- methylbut-3-en-2-yl)...

Synonyms: Tocris-1819, AC1MHXGL, CHEMBL18879, CHEMBL245012, SureCN304445, ...
 
 
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High impact information on DMAQ-B1

  • This effort led to the identification of a nonpeptidyl, small molecule, insulin-mimetic compound (demethylasterriquinone B-1, DMAQ-B1) that was isolated from a mixture of metabolites produced by a tropical endophytic fungus, Pseudomassaria sp. This compound induced human IRTK activation and increased tyrosine phosphorylation of IR beta subunit [1].

References

  1. Discovery of a small molecule insulin receptor activator. Salituro, G.M., Pelaez, F., Zhang, B.B. Recent Prog. Horm. Res. (2001) [Pubmed]
 
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