Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

CI-680 2-hydroxypropane-1,2,3- tricarboxylic acid;...

Synonyms: CI 680, AC1MI2GK, 56287-31-1, UNII-0X76UOC3KR

This record was replaced with 3037195.

Ferguson, E.R. et al.

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High impact information on CI 680

Changes in the chemical structures of these anti-estrogens produce compounds with markedly different affinities for the uterine estrogen receptor as measured in an in vitro cell-free cytosol system; binding affinities relative to estradiol (100%) are: CI-628, 4%; CI-680, 34%; 94X1127 (94X),222%; U-11,100A (UA), 6%; and U-23,469 (U-23), 0.1% [1].

References

A comparative study of antiestrogen action: temporal patterns of antagonism of estrogen stimulated uterine growth and effects on estrogen receptor levels. Ferguson, E.R., Katzenellenbogen, B.S. Endocrinology (1977) [Pubmed]

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