Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

CHEMBL103955 (Z)-2-methyl-3-tetradecyl- but-2-enedioic acid

Synonyms: CHEBI:266137, DNC004009, AC1MI36H, 148796-51-4, Chaetomellic acid A, ...

Singh, S.B. et al.

Singh, Jayasuriya, Silverman, Bonfiglio, Williamson, Lingham,

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High impact information on Chaetomellic acid A

Chaetomellic acid A inhibited human and yeast FPTase activity with IC50 values of 55 nM and 225 microM, respectively [1].

References

Efficient syntheses, human and yeast farnesyl-protein transferase inhibitory activities of chaetomellic acids and analogues. Singh, S.B., Jayasuriya, H., Silverman, K.C., Bonfiglio, C.A., Williamson, J.M., Lingham, R.B. Bioorg. Med. Chem. (2000) [Pubmed]

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