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Chemical Compound Review:

Triflubazam 6-methyl-2-phenyl-10- (trifluoromethyl)-2,6...

Synonyms: Triflubazamum, SureCN635822, ORF-8063, CHEMBL2107285, WE352, ...

Nicholson, A.N. et al., Itil, T.M. et al., Alton, K.B. et al.

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Psychiatry related information on WE 352

4 Subjects reported impaired sleep with triflubazam (40 mg) (P less than 0.05), and a sense of less wakefulness the morning after ingestion of clobazam (10 and 20 mg) (P less than 0.01) and triflubazam (40 mg) (P less than 0.05) [1].

High impact information on WE 352

Comparative biotransformation of triflubazam in rats, dogs, and monkeys [2].

Analytical, diagnostic and therapeutic context of WE 352

Controlled clinical and quantitative EEG studies of triflubazam (ORF 8063) in patients with anxiety syndrome [3].

References

Effect of the 1,5-benzodiazepines, clobazam and triflubazam, on sleep in man. Nicholson, A.N., Stone, B.M., Clarke, C.H. British journal of clinical pharmacology. (1977) [Pubmed]
Comparative biotransformation of triflubazam in rats, dogs, and monkeys. Alton, K.B., Patrick, J.E., Shaw, C., McGuire, J.L. Drug Metab. Dispos. (1975) [Pubmed]
Controlled clinical and quantitative EEG studies of triflubazam (ORF 8063) in patients with anxiety syndrome. Itil, T.M., Akpinar, S., Fink, M., Polvan, N., Huque, M., Sungurbey, K. Current therapeutic research, clinical and experimental. (1976) [Pubmed]

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