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Chemical Compound Review

AC1L1QN6     1,2-dimethoxybenzene; 1,3...

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Disease relevance of DIMETHOXYBENZENE

  • FP-21399 is a novel compound of the bis(disulfonaphthalene) dimethoxybenzene class that blocks entry of HIV into CD4+ cells and blocks fusion of infected and noninfected CD4+ cells [1].

High impact information on DIMETHOXYBENZENE


  1. FP-21399 blocks HIV envelope protein-mediated membrane fusion and concentrates in lymph nodes. Ono, M., Wada, Y., Wu, Y., Nemori, R., Jinbo, Y., Wang, H., Lo, K.M., Yamaguchi, N., Brunkhorst, B., Otomo, H., Wesolowski, J., Way, J.C., Itoh, I., Gillies, S., Chen, L.B. Nat. Biotechnol. (1997) [Pubmed]
  2. Elevated level of methylglyoxal during diabetic ketoacidosis and its recovery phase. Turk, Z., Nemet, I., Varga-Defteardarović, L., Car, N. Diabetes Metab. (2006) [Pubmed]
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