Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

CHEMBL125602 1,3-dichloro-5-phenyl-benzene

Synonyms: SureCN308200, PCB 14, AG-F-19752, CHEBI:34326, AC1L1WRO, ...

Havel, J. et al., Marchesini, G.R. et al.

Marchesini, Meulenberg, Haasnoot, Mizuguchi, Irth,

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Disease relevance of 3,5-Dichlorobiphenyl

When both sets of enzyme sequences were combined in one organism, Pseudomonas cepacia strain JH230, by conjugative transfer of genes of the biphenyl degradation sequence, the total degradation of 2-chloro-, 3-chloro-, 4-chloro-, 2,4-dichloro-, and 3,5-dichlorobiphenyl was achieved [1].

High impact information on 3,5-Dichlorobiphenyl

The chosen compounds were halogenated phenols, halogenated bisphenols, bisphenol A, 3,5-dichlorobiphenyl, and its hydroxylated metabolite 4-hydroxy-3,5-dichlorobiphenyl (4-OH PCB 14) [2].

References

Total degradation of various chlorobiphenyls by cocultures and in vivo constructed hybrid pseudomonads. Havel, J., Reineke, W. FEMS Microbiol. Lett. (1991) [Pubmed]
Biosensor recognition of thyroid-disrupting chemicals using transport proteins. Marchesini, G.R., Meulenberg, E., Haasnoot, W., Mizuguchi, M., Irth, H. Anal. Chem. (2006) [Pubmed]

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