Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Chemical Compound Review:

AMP-Amidate amino-[[(2R,3S,4R,5R)-5-(6- aminopurin-9...

Synonyms: AMP-NH2, CHEMBL583986, SureCN1835414, CHEBI:16771, AC1L98RD, ...

Kuriyama, H. et al., Bieganowski, P. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on AMP

Here we show that rabbit and yeast Hint hydrolyze the natural product adenosine-5'-monophosphoramidate (AMPNH(2)) in an active-site-dependent manner at second order rates exceeding 1,000,000 m(-1) s(-1) [1].
In the rabbit mesenteric artery, ATP and adenyl-imidophosphate showed much the same potency in inhibiting the amplitude of e.j.p.s. Therefore, the ATP action on nerve terminals is not due to a high energy requiring mechanism [2].

References

Adenosine monophosphoramidase activity of Hint and Hnt1 supports function of Kin28, Ccl1, and Tfb3. Bieganowski, P., Garrison, P.N., Hodawadekar, S.C., Faye, G., Barnes, L.D., Brenner, C. J. Biol. Chem. (2002) [Pubmed]
The presynaptic regulation of noradrenaline release differs in mesenteric arteries of the rabbit and guinea-pig. Kuriyama, H., Makita, Y. J. Physiol. (Lond.) (1984) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

Editor

Share