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Chemical Compound Review:

Imidine 4-ethanoyl-1-[(2R,5R)-4- hydroxy-5...

Synonyms: AC1LAJS9, AG-J-05158, CTK7J7672

Komoriya, K. et al., Kalman, T.I. et al.

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Disease relevance of Imidine

Mechanism of inhibition of HIV reverse transcriptase by 1-(2-deoxy-beta-D-ribofuranosyl)-4-acetylimidazolin-2-one (imidine) [1].

High impact information on Imidine

TI-31 (TEI-3096, 6-p-chlorobenzyl-5H-2,3,6,7-tetrahydro-5,7-dioxothiazolo[3,2-a]pyr imidine) reduced bovine type II collagen-induced arthritis (CIA) in rats in a time- and dose-dependent manner [2].

References

Mechanism of inhibition of HIV reverse transcriptase by 1-(2-deoxy-beta-D-ribofuranosyl)-4-acetylimidazolin-2-one (imidine). Kalman, T.I., Sen, K., Jiang, X.J. Nucleosides Nucleotides (1999) [Pubmed]
Anti-arthritic and immunoregulatory effects of TI-31 on collagen-induced arthritis. Komoriya, K., Nagata, I., Kunisawa, K., Takeshita, T., Naruchi, T. Jpn. J. Pharmacol. (1987) [Pubmed]

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