The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Chemical Compound Review


Synonyms: Naloxona, naloxone, Nalossone, Naloxonum, Nalone, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of naloxone

  • The present study suggests that naloxone may be clinically useful in the treatment of pain associated with sickle cell disease and other disorders involving inflammation [1].

Associations of naloxone with other chemical compounds

  • These data suggest that morphine may enhance naloxone CPA by increasing levels of constitutively active mu receptors and further support the role of such constitutive activity in mediating naloxone-precipitated physical withdrawal [2].


  1. Naloxone acts as a potent analgesic in transgenic mouse models of sickle cell anemia. Lunzer, M.M., Yekkirala, A., Hebbel, R.P., Portoghese, P.S. Proc. Natl. Acad. Sci. U.S.A. (2007) [Pubmed]
  2. Constitutively active micro opioid receptors mediate the enhanced conditioned aversive effect of naloxone in morphine-dependent mice. Shoblock, J.R., Maidment, N.T. Neuropsychopharmacology (2006) [Pubmed]
WikiGenes - Universities