Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

COELENTERAMIDE N-[3-benzyl-5-(4-oxo-1- cyclohexa-2,5...

Synonyms: SureCN134644, CHEBI:41487, DB04049, AC1NS123, C15038, ...

Deng, L. et al.

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High impact information on COELENTERAMIDE

Also the H-bonding between His-22 and the coelenterazine found in the active photoprotein is preserved at the equivalent position of coelenteramide, confirming the proposed rapid excited state proton transfer that would lead to the excited state of the phenolate ion pair, which is responsible for the blue emission of bioluminescence [1].
The addition of Ca2+ produces a blue bioluminescence by triggering a decarboxylation reaction of protein-bound hydroperoxycoelenterazine to form the product, coelenteramide, in an excited state [1].

References

Crystal structure of a Ca2+-discharged photoprotein: implications for mechanisms of the calcium trigger and bioluminescence. Deng, L., Markova, S.V., Vysotski, E.S., Liu, Z.J., Lee, J., Rose, J., Wang, B.C. J. Biol. Chem. (2004) [Pubmed]

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