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Chemical Compound Review: 

AC1NSFNR     (3E)-3-[[4-(2- carboxyethylcarbamoyl) phenyl...

Synonyms: CHEMBL102265, CHEMBL1201346, AC-13115, AK-51728, V0740, ...
 
 
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Disease relevance of BALSALAZIDE

  • 5-[4-(2-Carboxyethylcarbamoyl)phenylazo]salicylic acid disodium salt dihydrate (CAS 80573-04-2, BX661A) is being developed as a therapeutic drug for ulcerative colitis [1].
 

High impact information on BALSALAZIDE

  • 5-[4-(2-Carboxyethylcarbamoyl)phenylazo]salicylic acid disodium salt dihydrate (CAS 80573-04-2, BX661A) is developed as a therapeutic agent for ulcerative colitis [2].

References

  1. Determination of the active moiety of BX661A, a new therapeutic agent for ulcerative colitis, by studying its therapeutic effects on ulcerative colitis induced by dextran sulfate sodium in rats. Kimura, I., Kawasaki, M., Nagahama, S., Matsuda, A., Kataoka, M., Kokuba, Y. Arzneimittel-Forschung. (1998) [Pubmed]
  2. Effects of BX661A, a new therapeutic agent for ulcerative colitis, on chemotaxis and reactive oxygen species production in polymorphonuclear leukocytes in comparison with salazosulfapyridine and its metabolite sulfapyridine. Kimura, I., Kawasaki, M., Matsuda, A., Kataoka, M., Kokurba, Y. Arzneimittel-Forschung. (1998) [Pubmed]
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