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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Chemical Compound Review: 

Permethrin, (1S-cis)-Isomer     (3-phenoxyphenyl)methyl (1S,3S)-3-(2,2...

Synonyms: CHEMBL601463, CPD-13115, LS-58637, ZINC01850377, AC1L1WG7, ...
 
 
 
 
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High impact information on 1S-cis-Permethrin

  • Schild analysis using competitive interaction of pyrethroid-stereospecific isomers demonstrated that the F1519W mutation and a previously known pyrethroid-resistance mutation, L993F in IIS6, reduced the binding affinity of 1S-cis-permethrin, an inactive isomer that shares the same binding site with the active isomer 1R-cis-permethrin [1].

References

  1. Identification of amino acid residues in the insect sodium channel critical for pyrethroid binding. Tan, J., Liu, Z., Wang, R., Huang, Z.Y., Chen, A.C., Gurevitz, M., Dong, K. Mol. Pharmacol. (2005) [Pubmed]
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