Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

Mipragoside propan-2-yl (2R,4R,5S,6S)-5-acetamido-2...

Synonyms: Mipragosido, Mipragosidum, AC1O5L81, 131129-98-1, Ganglioside agf44, ...

Bucolo, C. et al., Centofanti, M. et al.

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Disease relevance of Mipragoside

Efficacy of mipragoside ophthalmic gel in vernal keratoconjunctivitis [1].
We evaluated the pharmacodynamic and pharmacokinetic profile of Mipragoside, a monosialoganglioside isopropyl-ester (as 0.5% w/w ophthalmic gel), on allergic inflammation of the eye induced by reverse passive Arthus reaction, on a non-immune mast cell degranulation elicited by compound 48/80 and on ocular inflammation produced by horse serum [2].

References

Efficacy of mipragoside ophthalmic gel in vernal keratoconjunctivitis. Centofanti, M., Schiavone, M., Lambiase, A., Taffara, M., Giuffrida, S., Bonini, S. Eye (London, England) (1996) [Pubmed]
Effects of Mipragoside on ocular allergic inflammation in the rabbit. Bucolo, C., Campana, G., Spadaro, A., Mangiafico, S. Journal of ocular pharmacology. (1993) [Pubmed]

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