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Chemical Compound Review

AC1O573T     azane; ruthenium(+3) cation

Synonyms: 55852-53-4, azane; ruthenium(3+), Pentaammineruthenium(3+), Pentaammineruthenium(III), Ruthenium(3+), pentaammine-, ...
 
 
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Disease relevance of Pentaammineruthenium chloride

  • Against Jurkat Tag cells, the toxicity of the pentaammineruthenium(III) group is enhanced by approximately two orders of magnitude upon binding primarily to the Fe-sites in apotransferrin, whereas the toxicity of the tetraammineruthenium(III) moiety is only marginally increased [1].
 

High impact information on Pentaammineruthenium chloride

References

  1. Cellular effects of transferrin coordinated to. Frasca, D.R., Gehrig, L.E., Clarke, M.J. J. Inorg. Biochem. (2001) [Pubmed]
  2. Quenching of intrinsic fluorescence of yeast cytochrome c peroxidase by covalently- and noncovalently-bound quenchers. Fox, T., Ferreira-Rajabi, L., Hill, B.C., English, A.M. Biochemistry (1993) [Pubmed]
 
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