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Chemical Compound Review:

AC1O5AS5 (2R,3R)-2,3- dihydroxybutanedioic acid; 2...

Synonyms: 65295-26-3

Pigini, M. et al., Pigini, M. et al.

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High impact information on Tracizoline

A series of 2-trans-styryl-imidazoline (tracizoline) congeners were designed and tested to develop 2-D and 3-D QSAR models for their binding to imidazoline (I2) receptor [1].
Imidazoline receptors: qualitative structure-activity relationships and discovery of tracizoline and benazoline. Two ligands with high affinity and unprecedented selectivity [2].

References

Ligand binding to I2 imidazoline receptor: the role of lipophilicity in quantitative structure-activity relationship models. Pigini, M., Bousquet, P., Brasili, L., Carrieri, A., Cavagna, R., Dontenwill, M., Gentili, F., Giannella, M., Leonetti, F., Piergentili, A., Quaglia, W., Carotti, A. Bioorg. Med. Chem. (1998) [Pubmed]
Imidazoline receptors: qualitative structure-activity relationships and discovery of tracizoline and benazoline. Two ligands with high affinity and unprecedented selectivity. Pigini, M., Bousquet, P., Carotti, A., Dontenwill, M., Giannella, M., Moriconi, R., Piergentili, A., Quaglia, W., Tayebati, S.K., Brasili, L. Bioorg. Med. Chem. (1997) [Pubmed]

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