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Chemical Compound Review:

Arduan [ (2S,3S,5S,8R,9S,10S,13S,14S,16 S,17S)-17...

Synonyms: SureCN42154, Arduan (TN), RGH-1106, CHEMBL1200722, RGH 1106, ...

This record was replaced with 50192.

Cholnoky, E., Tassonyi, E. et al.

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Disease relevance of Pipecurium

Acute toxicity studies with 2 beta,16 beta-bis(4'-dimethyl-1'-piperazino)-3 alpha,17 beta-diacetoxy-5 alpha-androstane dibromide (pipecurium bromide, RGH-1106, Arduan), a new neuromuscular blocking agent, revealed an order of sensitivity as follows: rabbits greater than mice greater than rats [1].

High impact information on Pipecurium

The pharmacokinetics of 2 beta, 16 beta-bis-(4'-dimethyl-1'-piperazino)-3 alpha, 17 beta-diacetoxy-5 alpha-androstane dibromide (pipecurium bromide, Arduan), a new non-depolarizing neuromuscular blocking agent, was studied in surgical patients [2].

References

Summary of safety tests with pipecurium bromide, a new neuromuscular blocking agent. Cholnoky, E. Arzneimittel-Forschung. (1980) [Pubmed]
Pharmacokinetics of pipecurium bromide, a new non-depolarizing neuromuscular blocking agent, in humans. Tassonyi, E., Szabó, G., Vereczkey, L. Arzneimittel-Forschung. (1981) [Pubmed]

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