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Chemical Compound Review

SureCN11806721     methylN-[2-[3- (methoxycarbonylamino)pheny...

Synonyms: NSC-251635, AC1L2ISE, NSC251635, AR-1J6381, NSC 251635, ...
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Disease relevance of NSC251635

  • In vivo, after ip or iv injections to CDF1 mice bearing intraperitoneal or intravenous L1210 leukemia, NSC-251635 was active only when it was incorporated in the liposomes and not when it was given as a suspension in Klucel or in saline [1].

Analytical, diagnostic and therapeutic context of NSC251635


  1. Antitumor activity of a water-insoluble compound entrapped in liposomes on L1210 leukemia in mice. Brassinne, C., Atassi, G., Frühling, J., Penasse, W., Coune, A., Hildebrand, J., Ruysschaert, J.M., Laduron, C. J. Natl. Cancer Inst. (1983) [Pubmed]
  2. Intravenous infusion of high doses of liposomes containing NSC 251635, a water-insoluble cytostatic agent. A pilot study with pharmacokinetic data. Sculier, J.P., Coune, A., Brassinne, C., Laduron, C., Atassi, G., Ruysschaert, J.M., Frühling, J. J. Clin. Oncol. (1986) [Pubmed]
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