Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

TCAD [[(2R,3S,4R,5R)-5-(4- aminocarbonyl-1,3...

Synonyms: CHEMBL394276, CHEBI:504059, KST-1A8720, AC1L2KAD, DNC007867, ...

Franchetti, P. et al., Marquez, V.E. et al.

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High impact information on Adenosine 5'-(trihydrogen diphosphate), 5'-5'-ester with 2-beta-D-ribofuranosyl-4-thiazolecarboxamide

Thiazole-4-carboxamide adenine dinucleotide (TAD). Analogues stable to phosphodiesterase hydrolysis [1].
Synthesis, conformational analysis, and biological activity of new analogues of thiazole-4-carboxamide adenine dinucleotide (TAD) as IMP dehydrogenase inhibitors [2].

References

Thiazole-4-carboxamide adenine dinucleotide (TAD). Analogues stable to phosphodiesterase hydrolysis. Marquez, V.E., Tseng, C.K., Gebeyehu, G., Cooney, D.A., Ahluwalia, G.S., Kelley, J.A., Dalal, M., Fuller, R.W., Wilson, Y.A., Johns, D.G. J. Med. Chem. (1986) [Pubmed]
Synthesis, conformational analysis, and biological activity of new analogues of thiazole-4-carboxamide adenine dinucleotide (TAD) as IMP dehydrogenase inhibitors. Franchetti, P., Cappellacci, L., Pasqualini, M., Petrelli, R., Jayaprakasan, V., Jayaram, H.N., Boyd, D.B., Jain, M.D., Grifantini, M. Bioorg. Med. Chem. (2005) [Pubmed]

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