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Chemical Compound Review:

ARONIS23888 ethyl 2-cyanoethanoate

Synonyms: NSC-8844, ACMC-1BVYH, E18425_ALDRICH, AG-K-67786, ANW-15243, ...

Stauffer, S.R. et al., Montgomery, G.J. et al.

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High impact information on Cyanacetate ethyle

Palladium-catalyzed arylation of ethyl cyanoacetate. Fluorescence resonance energy transfer as a tool for reaction discovery [1].
The most active compound, 12, formed from 7-quinolinecarbaldehyde and ethyl cyanoacetate, had an IC50 value of 2.3 microM [2].

References

Palladium-catalyzed arylation of ethyl cyanoacetate. Fluorescence resonance energy transfer as a tool for reaction discovery. Stauffer, S.R., Beare, N.A., Stambuli, J.P., Hartwig, J.F. J. Am. Chem. Soc. (2001) [Pubmed]
Synthesis and antiproliferative activity of unsaturated quinoline derivatives. Montgomery, G.J., McKeown, P., McGown, A.T., Robins, D.J. Anticancer Drug Des. (2000) [Pubmed]

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