Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

CHEMBL476636 2,3-dichloro-1,1,1,2,3,4,4,4- octafluoro...

Synonyms: ACMC-1CPCX, AG-F-23026, ACMC-20dh57, NSC-76604, AC1Q4HNU, ...

Minami, K. et al., Raines, D.E. et al.

Raines, Claycomb, Forman,

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Psychiatry related information on NSC76604

At concentrations predicted to be anesthetic, 1,2-dichlorohexafluorocyclobutane and 2,3-dichlorooctafluorobutane produce amnesia but fail to produce immobility [1].

High impact information on NSC76604

The nonanesthetics 1, 2-dichlorohexafluorocyclobutane and 2,3-dichlorooctafluorobutane had no effect on the functions of either wild-type GluR6 or receptors mutated at Gly-819 [2].

References

Nonhalogenated anesthetic alkanes and perhalogenated nonimmobilizing alkanes inhibit alpha(4)beta(2) neuronal nicotinic acetylcholine receptors. Raines, D.E., Claycomb, R.J., Forman, S.A. Anesth. Analg. (2002) [Pubmed]
Sites of volatile anesthetic action on kainate (Glutamate receptor 6) receptors. Minami, K., Wick, M.J., Stern-Bach, Y., Dildy-Mayfield, J.E., Brozowski, S.J., Gonzales, E.L., Trudell, J.R., Harris, R.A. J. Biol. Chem. (1998) [Pubmed]

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