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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Chemical Compound Review: 

Koolizer 1     N,N,N',N'-tetramethylhexane- 1,6-diamine

Synonyms: Toyocat MR, Minico TMHD, CHEMBL118765, ACMC-1C25E, AG-D-29293, ...
 
 
 
 
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Disease relevance of Koolizer 1

  • In the other 6 products, FIXa content ranged from 0.15-1.2 U/1000 in FIX, and all showed some evidence of in vivo thrombogenicity, with mean thrombus scores ranging from 0.25-4 [1].

References

  1. Measurement of activated factor IX in factor IX concentrates: correlation with in vivo thrombogenicity. Gray, E., Tubbs, J., Thomas, S., Oates, A., Boisclair, M., Kemball-Cook, G., Barrowcliffe, T.W. Thromb. Haemost. (1995) [Pubmed]
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