Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

CCRIS 343 3-hydroxy-7H-purine-2,6-dione

Synonyms: SureCN864455, NSC-145424, NSC-529141, AC1Q6LKG, CTK3I8958, ...

Michael, R.O. et al., Anderson, L.M. et al.

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High impact information on N-Hydroxyxanthine

Increased incidence of mammary tumors in rats after direct or transplacental exposure to 3-hydroxyxanthine [1].
Liver DNA from rats given 3-hydroxyxanthine (100 mug/g for 4 h) or calf thymus DNA incubated in vitro with this carcinogen did not show any change in their melting profile [2].

References

Increased incidence of mammary tumors in rats after direct or transplacental exposure to 3-hydroxyxanthine. Anderson, L.M., Teller, M.N., Budinger, J.M., Brown, G.B. J. Natl. Cancer Inst. (1978) [Pubmed]
In vivo repair of rat liver DNA damaged by 3-hydroxyxanthine. Michael, R.O., Parodi, S., Sarma, D.S. Chem. Biol. Interact. (1975) [Pubmed]

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