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Chemical Compound Review:

Agent I 3-chloro-4,4-dimethyl-1,3- oxazolidin-2-one

Synonyms: AG-G-07608, CHEMBL1770164, CTK5A8620, AR-1F2587, AC1L3NY7, ...

Barnela, S.B. et al., Elder, E.D. et al.

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Disease relevance of Agent I

The stabilities and disinfection efficacies against Staphylococcus aureus of the compounds in water solution are compared with those for 3-chloro-4,4-dimethyl-2-oxazolidinone which has been studied extensively in recent years in these laboratories and elsewhere [1].

High impact information on Agent I

Agent I (3-chloro-4,4-dimethyl-2-oxazolidinone) formed in situ was compared with pre-formed agent I as a disinfectant against Staphylococcus aureus [2].

References

Syntheses and antibacterial activity of new N-halamine compounds. Barnela, S.B., Worley, S.D., Williams, D.E. Journal of pharmaceutical sciences. (1987) [Pubmed]
Bactericidal properties of an organic N-chloramine formed in situ. Elder, E.D., Worley, S.D., Williams, D.E. J. Appl. Bacteriol. (1987) [Pubmed]

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