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Chemical Compound Review:

C09952 (6R)-6-(2-benzo[1,3]dioxol-5- ylethenyl)-4...

Synonyms:

Schmitz, D. et al., Anke, J. et al.

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High impact information on C09952

Effects of methysticin on three different models of seizure like events studied in rat hippocampal and entorhinal cortex slices [1].
Decreases in [Ca2+]0 and associated slow field potentials evoked by repetitive stimulation of the stratum radiatum or the alveus remained almost unaffected by methysticin [1].
Four kavalactones, (+/-)-kavain, methysticin, yangonin and desmethoxyyangonin, fail to inhibit ADH in vitro at 1, 10 or 100 microM concentrations [2].

References

Effects of methysticin on three different models of seizure like events studied in rat hippocampal and entorhinal cortex slices. Schmitz, D., Zhang, C.L., Chatterjee, S.S., Heinemann, U. Naunyn Schmiedebergs Arch. Pharmacol. (1995) [Pubmed]
Kavalactones fail to inhibit alcohol dehydrogenase in vitro. Anke, J., Fu, S., Ramzan, I. Phytomedicine (2006) [Pubmed]

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