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Chemical Compound Review

Lopac-A-7250     (2R)-2-acetamido-3-sulfanyl- propanoic acid

Synonyms: AG-E-81312, KBioSS_000384, NINDS_000530, NSC-755856, CTK1A3007, ...
 
 
 
 
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High impact information on Lopac-A-7250

  • Similar effects on DNA fragmentation were obtained when the experiments were repeated in the presence either of a specific inhibitor of GSH biosynthesis (buthionine sulfoximine) or the isomer N-acetyl-D-cysteine which cannot be enzymatically converted into GSH [1].

References

  1. Effects of N-acetyl-L-cysteine on T-cell apoptosis are not mediated by increased cellular glutathione. Jones, D.P., Maellaro, E., Jiang, S., Slater, A.F., Orrenius, S. Immunol. Lett. (1995) [Pubmed]
 
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