Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Chemical Compound Review:

HFBI 2,2,3,3,4,4,4-heptafluoro-1- imidazol-1-yl...

Synonyms: PubChem6488, AG-F-08595, H9903_SIGMA, ANW-27359, NSC-151966, ...

Krishnamurthy, T. et al., Cummins, K.J. et al., Phillips, L.R. et al., Preu, M. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on n-Heptafluorobutyrylimidazole

The analytes were derivatised using a two-step procedure involving trimethylsilylation of the hydroxyl groups with trimethylsilylimidazole and acylation of the amino groups with heptafluorobutyrylimidazole [1].
Sample analysis is performed by gas chromatography with electron capture detection (GC/ECD) following desorption with dimethylformamide (DMF) and derivatization of the 2-bromoethanol reaction product with heptafluorobutyrylimidazole (HFBI) [2].
The procedure involves the conversion of the molecules to their corresponding alcohols (verrucarols) by alkaline hydrolysis, followed by derivatization of the hydrolysate with heptafluorobutyrylimidazole and analysis by GC/MS technique under negative ion chemical ionization conditions [3].

Analytical, diagnostic and therapeutic context of n-Heptafluorobutyrylimidazole

The residue afforded by evaporation of the organic solvent is dried in vacuo and derivatized with heptafluorobutyrylimidazole prior to analysis by capillary gas chromatography with electron capture detection [4].

References

Development of a gas chromatography-mass spectrometry method for the analysis of aminoglycoside antibiotics using experimental design for the optimisation of the derivatisation reactions. Preu, M., Guyot, D., Petz, M. Journal of chromatography. A. (1998) [Pubmed]
The development and evaluation of a hydrobromic acid-coated sampling tube for measuring occupational exposures to ethylene oxide. Cummins, K.J., Schultz, G.R., Lee, J.S., Nelson, J.H., Reading, J.C. American Industrial Hygiene Association journal. (1987) [Pubmed]
Mass spectral investigations on trichothecene mycotoxins. II. Detection and quantitation of macrocyclic trichothecenes by gas chromatography/negative ion chemical ionization mass spectrometry. Krishnamurthy, T., Sarver, E.W., Greene, S.L., Jarvis, B.B. Journal - Association of Official Analytical Chemists. (1987) [Pubmed]
Analysis of brefeldin A in plasma by gas chromatography with electron capture detection. Phillips, L.R., Supko, J.G., Malspeis, L. Anal. Biochem. (1993) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

Editor

Share