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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Chemical Compound Review: 

EGFR Inhibitor     N-[3-[[6-[[3- (trifluoromethyl) phenyl]amino...

Synonyms: CHEMBL387187, SureCN242230, CHEBI:463054, CTK8E9808, HMS3229E03, ...
 
 
 
 
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Disease relevance of EGFR Inhibitor

  • These results suggest that STAT3 activation contributes to EGFR inhibitor resistance both in HNSCC and bladder cancer where concomitant targeting of STAT3 may represent an effective treatment strategy [1].

References

  1. Targeting Stat3 Abrogates EGFR Inhibitor Resistance in Cancer. Sen, M., Joyce, S., Panahandeh, M., Li, C., Thomas, S.M., Maxwell, J., Wang, L., Gooding, W.E., Johnson, D.E., Grandis, J.R. Clin. Cancer Res. (2012) [Pubmed]
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