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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Gpr153  -  G protein-coupled receptor 153

Mus musculus

Synonyms: 1110065N12Rik, AI449320, G-protein coupled receptor PGR1, PGR1, Pgr1
 
 
 
 
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Disease relevance of Gpr153

  • Identification of signaling elements downstream of COX inhibition, particularly of PG receptor subtypes responsible for pain sensitization (hyperalgesia), provides a strategy for better-tolerated analgesics [1].

References

  1. Spinal inflammatory hyperalgesia is mediated by prostaglandin E receptors of the EP2 subtype. Reinold, H., Ahmadi, S., Depner, U.B., Layh, B., Heindl, C., Hamza, M., Pahl, A., Brune, K., Narumiya, S., Müller, U., Zeilhofer, H.U. J. Clin. Invest. (2005) [Pubmed]
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