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Gene Review:

comE - response regulator of the competence...

Streptococcus mutans UA159

Li, Y.H. et al., Ahn, S.J. et al.

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High impact information on comE

Inactivation of comE or comD had no effect on stress tolerance, but transformability of the mutants was poor and was not restored by addition of competence-stimulating peptide (CSP) [1].

Associations of comE with chemical compounds

The genetic locus of this system comprises three genes, comC, comD, and comE, that encode a precursor to the peptide competence factor, a histidine kinase, and a response regulator, respectively [2].

References

Multilevel control of competence development and stress tolerance in Streptococcus mutans UA159. Ahn, S.J., Wen, Z.T., Burne, R.A. Infect. Immun. (2006) [Pubmed]
Natural genetic transformation of Streptococcus mutans growing in biofilms. Li, Y.H., Lau, P.C., Lee, J.H., Ellen, R.P., Cvitkovitch, D.G. J. Bacteriol. (2001) [Pubmed]

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