Gene Review:
rnpB - miscRNA
Escherichia coli CFT073
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Disease relevance of rnpB
- Mutant RNase P RNA alleles (rnpBC292 and rnpBC293) caused severe growth defects in the E. coli rnpB mutant strain DW2 and abolished growth in the newly constructed mutant strain BW, in which chromosomal rnpB expression strictly depended on the presence of arabinose [1].
References
- The precursor tRNA 3'-CCA interaction with Escherichia coli RNase P RNA is essential for catalysis by RNase P in vivo. Wegscheid, B., Hartmann, R.K. RNA (2006) [Pubmed]
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