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Gene Review

N4BP2L2  -  NEDD4 binding protein 2-like 2

Homo sapiens

Synonyms: 92M18.3, CG005, NEDD4-binding protein 2-like 2, PFAAP5, Phosphonoformate immuno-associated protein 5
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High impact information on PFAAP5

  • Reduced expression of Wip1 and BRCA-2 region transcription unit CG005 was significantly correlated with poorer differentiation of HCCs, and mRNA expression of these genes was significantly reduced in HCCs associated with portal vein involvement compared with HCCs without such involvement [1].


  1. MRNA expression of genes altered by 5-azacytidine treatment in cancer cell lines is associated with clinicopathological parameters of human cancers. Kanai, Y., Ushijima, S., Saito, Y., Nakanishi, Y., Sakamoto, M., Hirohashi, S. J. Cancer Res. Clin. Oncol. (2001) [Pubmed]
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