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Gene Review

COG5  -  component of oligomeric golgi complex 5

Homo sapiens

Synonyms: 13S Golgi transport complex 90 kDa subunit, CDG2I, COG complex subunit 5, Component of oligomeric Golgi complex 5, Conserved oligomeric Golgi complex subunit 5, ...
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High impact information on COG5

  • Genetic analysis of the subunit organization and function of the conserved oligomeric golgi (COG) complex: studies of COG5- and COG7-deficient mammalian cells [1].
  • Large-scale immunoprecipitation of rat liver cytosol with immobilized anti-Sec34 antibodies has co-immunoprecipitated GTC-90 and ldlBp, two peripheral Golgi proteins previously shown to exist in separate protein complexes [2].

Anatomical context of COG5


Other interactions of COG5

  • These results suggest that Sec34, GTC-90, and ldlBp/ldlCp are part of the same protein complex(es) that regulates diverse aspects of Golgi function, including transport from the ER to the Golgi apparatus [2].


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