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Gene Review:

ST6GALNAC2 - ST6 (alpha-N-acetyl-neuraminyl-2,3-beta...

Homo sapiens

Synonyms: Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2, GalNAc alpha-2,6-sialyltransferase II, SAITL1, SIAT7, SIAT7-B, ...

Sotiropoulou, G. et al.

Sotiropoulou, Kono, Anisowicz, Stenman, Tsuji, Sager,

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Disease relevance of ST6GALNAC2

However, Southern analyses indicated that SIATL1 is usually not grossly rearranged in breast tumors [1].

High impact information on ST6GALNAC2

The chromosomal localization of the SIATL1 gene was assigned by somatic cell hybrid analysis [1].
The SIATL1 gene, encoding STM, was mapped to the long arm of human chromosome 17 at q23-qter, a region that is nonrandomly deleted in human breast cancers [1].

References

Identification and functional characterization of a human GalNAc [alpha]2,6-sialyltransferase with altered expression in breast cancer. Sotiropoulou, G., Kono, M., Anisowicz, A., Stenman, G., Tsuji, S., Sager, R. Mol. Med. (2002) [Pubmed]

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