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Gene Review

Ssq  -  sasquatch

Mus musculus

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High impact information on Ssq

  • These data strongly suggest that Ssq is caused by direct interference with the cis regulation of the Shh gene [1].
  • We generated, by a transgene insertion event, a new member of this group of mutants, Sasquatch (Ssq), which disrupted aspects of both anteroposterior (AP) and dorsoventral (DV) patterning [1].


  1. Identification of sonic hedgehog as a candidate gene responsible for the polydactylous mouse mutant Sasquatch. Sharpe, J., Lettice, L., Hecksher-Sorensen, J., Fox, M., Hill, R., Krumlauf, R. Curr. Biol. (1999) [Pubmed]
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