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Gene Review: 

Tthy  -  thymocyte alloantigen

Mus musculus

 
 
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High impact information on Tthy

  • Tpre and Tthy are expressed on largely overlapping cell populations in adult thymus [1].
  • The purpose of this study was to determine if the Tthy-bearing cell is a precursor for cells in the periphery expressing Tind and Tsu [2].
  • Tthyd, a new thymocyte alloantigen linked to Igh-1. Implications for a switch mechanism for T cell antigen receptors [3].

References

  1. Tpre, a new alloantigen encoded in the IgT-C region of chromosome 12, is expressed on bone marrow of nude mice, fetal T cell hybrids, and fetal thymus. Owen, F.L. J. Exp. Med. (1983) [Pubmed]
  2. Modulation of Tthy alloantigen expression in the neonatal mouse. The Tthy-bearing thymocyte is a precursor for the peripheral cells expressing Tind and Tsu. Keesee, S.K., Owen, F.L. J. Exp. Med. (1983) [Pubmed]
  3. Tthyd, a new thymocyte alloantigen linked to Igh-1. Implications for a switch mechanism for T cell antigen receptors. Owen, F.L., Spurll, G.M., Panageas, E. J. Exp. Med. (1982) [Pubmed]
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