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Gene Review

Mis2  -  Mo-MuLV integration site 2

Mus musculus

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Disease relevance of Mis2

  • Using cellular sequences flanking a provirus cloned from one of these tumors, we found one region, designated Mis-2, which was the target of provirus integration in a low (3%) percentage of these tumors [1].

High impact information on Mis2

  • In addition, another previously identified provirus insertion site, Mis-2, was found to map within the 16th intron of the Ahi-1 gene [2].
  • Mis-2 was mapped on mouse chromosome 10, approximately 160 kbp downstream of myb [1].


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