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Gene Review

OSBPL8  -  oxysterol binding protein-like 8

Homo sapiens

Synonyms: KIAA1451, MST120, MSTP120, ORP-8, ORP8, ...
 
 
 
 
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Regulatory relationships of OSBPL8

  • Experiments employing an ABCA1 promoter-luciferase reporter confirmed that ORP8 silencing enhances ABCA1 transcription [1].

References

  1. OSBP-related protein 8 (ORP8) suppresses ABCA1 expression and cholesterol efflux from macrophages. Yan, D., Mäyränpää, M.I., Wong, J., Perttilä, J., Lehto, M., Jauhiainen, M., Kovanen, P.T., Ehnholm, C., Brown, A.J., Olkkonen, V.M. J. Biol. Chem. (2008) [Pubmed]
 
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