The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Gene Review

Tbrs1  -  tuberculosis resistance 1

Mus musculus

Synonyms: Tbrl1, Trl-1
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on Tbrs1

  • Quantitative trait locus mapping identified a major locus on chromosome 19 (Tuberculosis resistance locus-4, Trl-4; logarithm of odds 5.6), which regulated pulmonary replication of M. tuberculosis and accounted for 25% of the phenotypic variance [1].
  • QTL analysis identified two significant linkages on the distal portion of chromosome 1 (Trl-1, LOD, 4.80) and on the proximal portion of chromosome 7 (Trl-3, LOD, 4.66) that each account for approximately 21% of the phenotypic variance [2].


  1. Susceptibility to tuberculosis: a locus on mouse chromosome 19 (Trl-4) regulates Mycobacterium tuberculosis replication in the lungs. Mitsos, L.M., Cardon, L.R., Ryan, L., LaCourse, R., North, R.J., Gros, P. Proc. Natl. Acad. Sci. U.S.A. (2003) [Pubmed]
  2. Genetic control of susceptibility to infection with Mycobacterium tuberculosis in mice. Mitsos, L.M., Cardon, L.R., Fortin, A., Ryan, L., LaCourse, R., North, R.J., Gros, P. Genes Immun. (2000) [Pubmed]
WikiGenes - Universities